drugs causing pure red cell aplasia

Found inside – Page 495... of blood transfusion , 449 450 Pteroylglutamic acid see Folate Pure red cell aplasia , acquired / congenital , 231 - 233 ... 370 Prothrombin , congenital prothrombin Quinidine , causing neutropenia , 106 Quinine / quinidine drug - dependent ... Found insideThis book is a collection of expert assays on various aspects of HIV prevention, bioresource deployment, microbicides, host antiviral proteins, antiviral drug responses and novel treatment strategies for which there is evident need for ... Found insideFully-updated new edition of the essential guide to managing hematological conditions, affecting mother and baby during pregnancy and post-partum. Found insideGet the BIG PICTURE of Pathology - and focus on what you really need to know to score high on the course and board exam If you want a streamlined and definitive look at Pathology - one with just the right balance of information to give you ... Found inside – Page 414When an IV drug abuser is infected with the AIDS virus, parvovirus #B—19 can enter the bloodstream, resulting in pure red cell aplasia. Found inside – Page 233Rarely , pure red cell aplasia may occur . 3 Drugs that cause haemolysis because of the develCytotoxic drugs are the commonest cause . opment ... Found inside – Page 1957Auranofin - induced changes in bowel habits have been severe enough to require discontinuance of the drug in about 4_6 % of patients . ... I Renal Effects Like other gold compounds , auranofin may cause proteinuria ( and rarely nephrotic syndrome ) or membranous ... neutropenia in less than 1 % of patients , and agranulocytosis , pure red cell aplasia , pancytopenia , and aplastic anemia in less than ... Found inside – Page 185For example, only acquired pure red cell aplasia (D60) is coded here; ... the instructional note is to code the drug causing the anemia first. Health Sciences & Professions Found inside – Page 100It is therefore not surprising that studies of aplastic anaemia and pure red cell aplasia have identified immune abnormalities ... A or B ) , drug therapy , thymoma , or EBV infection causing the X - linked recessive lymphoproliferative syndrome . Found inside – Page 7872009) Pure red cell aplasia presents as that of normocytic anemia with ... Box 51.4 Drugs Causing Pure Red Cell Aplasia Azathioprine Antithymocyte Globulin ... Found inside – Page 185Hemolytic anemias, therefore, are anemias caused when red blood cells are destroyed ... of the d ug causing drug-induced hemolytic anemias (D590 and D592). Found inside – Page 241Rarely, pure red cell aplasia may occur. Cytotoxic drugs are the commonest cause. Drugs causing aplastic anaemia usually incorporate a benzene ring with ... Found insideThis book deals with a very common condition, anemia, which might interest not only the physicians but also other healthcare professionals and researchers dealing with anemic patients. Found inside – Page 605... significant enough to cause pure red blood cell aplasia (PRCA) with resultant profound anemia, arrest of erythropoiesis, and transfusion dependency. Found inside – Page 293Summary This chapter hopes to show that drug discovery is a long , complex process ... to recombinant human erythropoietin causing pure red cell aplasia . Found inside – Page 349... scarcity or absence of erythropoietic and myelopoietic precursor cells ; patients with pure red cell aplasia demonstrate ... of hemolytic anemias varies with the cause ( 1 ) Drug induced ( a ) Discontinue drug ( b ) Immunosuppressive treatment ... Particularly relevant for psychiatrists and trainees in psychiatry, this volume will also assist neurologists and general physicians who encounter psychosis in their practice. Found inside – Page 420This chapter will review the types of reaction by which drugs may cause ... selectively affect only one lineage [e.g. pure red cell aplasia (PRCA)]. Found inside – Page 200The antimetabolite azathioprine, a purine-analog drug, can also cause ... and anti-thymocyte globulin have all shown to cause pure red cell aplasia [19, ... Found inside – Page iiThis text provides a concise yet comprehensive overview of anemia in the young and old. Found inside – Page 1143Parvovirus B19 and hepatitis A or B may also cause neutropenia, but are more often associated with pure red cell aplasia or multiple ... Found inside – Page 206The acquired forms of pure red cell aplasia more frequently present with ... invades and replicates in erythroid progenitor cells, causing direct cytotoxic ... Found inside – Page xiiDrug Groups Associated with Acute Porphyria..........................................................729 ... Causes of Pure Red Cell Aplasia...... Found inside – Page 163... HIV Disease 163 Pure red cell aplasia ( PRCA ) is not uncommon . ... Other drugs causing anemia include hemolysis are a high reticulocyte count ... Found inside – Page 943... warm and cold agglutinins and hemolysins , 239 antinuclear antibodies , and antibodies causing false - positive serologic tests for syphilis . ... 2 lack any prognostic significance 225 Hematologic findings in pure red cell aplasia ( anemia ) Pure red cell aplasia is a selective ... in 50 % of patients with thymomas236 and following the administration of drugs such as chloramphenicol , phenytoin and others . Found inside – Page 117Pure red cell aplasia. WHO Pharmaceuticals Newslett 2002; 4: 7. [87] Anonymous. Darbepoetin alfa: profile report. Drugs Ther Perspect 2002; 18: 4–5. Found insideThere are case reports of valproic acid causing pure red cell aplasia, which resolves when the drug is discontinued (Bartakke et al. 2008). Found inside – Page 245Drugs Drugs have been associated with aplastic anemia. ... Between 1988 and 1998, antibody-associated pure red cell aplasia was reported in three patients ... Broken down into eight parts, this book provides readers with a comprehensive overview of: Laboratory Hematology, The Normal Hematologic System, Transfusion Medicine, Disorders of Red Cells, Hemostasis and Coagulation; Benign Disorders of ... Found inside – Page 110Pure red cell aplasia is divided into that without any suspected cause or drug induction and that with some suspected cause . The aplasia associated with ... Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013. Found inside – Page 122The stereotypical syndrome of posthepatitis aplasia would seem to offer the opportunity to ... Pure red cell aplasia is often associated with thymomas . Found inside – Page 948... congenital dyserythropoietic anaemia • pure red-cell aplasia • parvovirus ... Box 277.3 Some drugs and other toxic agents causing bone marrow failure ... Found inside – Page 365Antineoplastics Determining the drug causing the problem and stopping Fludarabine is ... nonsteroidal anti-inflammatory drugs; PRCA, pure red cell aplasia. Found inside – Page 500It is imperative to stop all medications that might be causing the marrow failure. Other forms of marrow failure include pure red cell aplasia, where marrow ... Found insideDecline in the need for blood transfusions in cancer patients due to the use ... C. Immunological reaction against erythropoietin causing red-cell aplasia. Found inside – Page 149Although many drugs have been implicated in causing pure red blood cell aplasia , an immunological mechanism has been established for only a few . Found inside – Page 809... A and B may also cause neutropenia,703,704 although they are more commonly associated with pure red cell aplasia and multiple cytopenias, respectively. Found insideResolution of pure red cell aplasia with continued production of low titer ... C. Immunological reaction against erythropoietin causing red-cell aplasia. Found inside – Page 109They sometimes cause convulsions, especially during the first 90 days of ... causing a lack of red blood cells called pure red cell aplasia (PRCA). Given that there have been considerable advances in the treatment and management of oncologic diseases in children, the fifth edition of this successful clinical manual will be entirely updated to incorporate all current protocols and ... Comprehensive and up-to-date clinical reference, with an emphasis on treatment. Found inside – Page 234Table 6.20 Some causes of anaemia of importance in the fetus and neonate. ... e.g. Rh or Kell antibodies, rarely ABO [233] Pure red cell aplasia caused ... Found inside – Page 445Impaired erythropoietin production causes a subnormal erythroid response to a reduction in hemoglobin concentration and is primarily responsible ... Pure red cell aplasia and congenital dyserythropoietic anemia, however, are probably caused by defects in the target cells, the ... and in others the red cell defect is so minimal that it demands exposure to a drug or an infection in order to become manifest. Found inside – Page 429Pure red - cell aplasia : acquired , 139 causes , 138–139 clinical manifestations , 40 congenital , 40 , 138 diagnosis of , 40 , 41 drug - induced , 139 hemolytic anemia and , 139 idiopathic , 139 infections causing , 139 malnutrition causing , 139 ... Found inside – Page 10Drug-induced pure red cell aplasia is due to an immune-based drug reaction. ... and therapeutic antibodies) and antibiotics are common causes. Many drugs ... 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